Re-sensitization
‘hacking tolerance’
When a drug is taken in high doses for a long time, the body develops a compensatory response – this means that when the brain detects the drug is about to kick in, it immediately induces the opposite effects to the drug, and the result is a weaker drug effect (drug tolerance).
The compensatory response is highly dose-dependent, which means tolerance develops to a certain dosage, and NOT to the drug overall.
Where it gets interesting is with very low doses of drugs. When very low doses of drugs are taken after a tolerance has developed, it causes a reversal of the compensatory response, making it increase the drug effects instead of decreasing them! It means that tolerance will become NEGATIVE, meaning the drug effect will be stronger than it was in the first time (where tolerance was 0).
If you have built a tolerance to a drug and want to resensinitize your system to it (increase your sensitivity to it and reduce tolerance), follow these steps:
- Take a 24 hour break from the drug. This is necessary to make sure the drug is at least out of your body and the effect is completely gone (drug half-life).
- Take 5% of your regular drug dose. The goal here is to feel the most minimal effect possible. If you don’t feel any effect after a while (wait at least 5 minutes), take again 5% of your regular dose.
- Repeat this process until the most minimal effect is felt. Once you feel the most minimal effect possible, stop taking it.
- Wait 12 hours after Stage 2. Once 12 hours have passed, take your regular dose. Your tolerance will be much lower and the effects will be significantly more pronounced.
- Whenever you feel tolerance building up again, you can repeat this process.
This method does work excellently, as confirmed by a few studies done on different drugs than meth, but it will work exactly the same for all kind of drugs including meth, and there are many anecdotal reports on the internet that tolerance is significantly reduced from taking very low doses of drugs
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Question how does the old stuff differ from the new stuff in ingredients and why did it change? I heard cheaper to make yet quality speaking…not worth it when you have to eat and sleep now where as both were impossible on the old and you didn’t feel like crap most of the time like now?
The answer can be found in another post: https://cook13.blue/mexican-meth-explained/
I’ve heard of this reverse tolerance, but never had it explained. That was very insightful. Thanks!!!